Hypotensive effect of mannitol administered rapidly

CM Domaingue, DH Nye - Anaesthesia and intensive care, 1985 - journals.sagepub.com
CM Domaingue, DH Nye
Anaesthesia and intensive care, 1985journals.sagepub.com
Mannitol is an osmotic diuretic commonly used to reduce intracranial pressure. While
various side-effects, including hyperosmolar states, precipitate reduction in intracranial
pressure, rebound phenomenon and hypervolaemia have been described, hypotension due
to rapid administration has not been widely recognised.
Mannitol is an osmotic diuretic commonly used to reduce intracranial pressure. While various side-effects, including hyperosmolar states, precipitate reduction in intracranial pressure, rebound phenomenon and hypervolaemia have been described, hypotension due to rapid administration has not been widely recognised.
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